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验证数据展示

  • WB analysis of human brain using 12390-1-AP (same clone as 12390-1-PBS)

    WB analysis of human brain using 12390-1-AP (same clone as 12390-1-PBS)

    human brain tissue were subjected to SDS PAGE followed by western blot with 12390-1-AP (BEX1/2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12390-1-PBS in a different storage buffer formulation.

  • IHC staining of human medulloblastoma using 12390-1-AP (same clone as 12390-1-PBS)

    IHC staining of human medulloblastoma using 12390-1-AP (same clone as 12390-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human medulloblastoma using 12390-1-AP (BEX1/2 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 12390-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with BEX1/2 antibody included

BEX1/2 Polyclonal antibody, PBS Only

BEX1/2 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 12390-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

BEX2, Brain-expressed X-linked protein 2, hBex2

缓冲液配方: 
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy BEX1/2 Ready-To-Use IHC Kit. BEX1/2 primary antibody included.

产品信息

12390-1-PBS targets BEX1/2 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag3066

Product name: Recombinant human BEX2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-128 aa of BC015522

Sequence: MESKEERALNNLIVENVNQENDEKDEKEQVANKGEPLALPLNVSEYCVPRGNRRRFRVRQPILQYRWDIMHRLGEPQARMREENMERIGEEVRQLMEKLREKQLSHSLRAVSTDPPHHDHHDEFCLMP

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 brain expressed X-linked 2
别名 BEX2, Brain-expressed X-linked protein 2, hBex2
计算分子量 128 aa, 15 kDa
观测分子量 10-15 kDa
GenBank蛋白编号BC015522
基因名称 BEX2
Gene ID (NCBI) 84707
RRIDAB_10644326
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9BXY8
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

BEX1 is a signaling adapter molecule involved in p75NTR/NGFR signaling. It lays a role in cell cycle progression and neuronal differentiation. BEX1 inhibits neuronal differentiation in response to nerve growth factor (NGF). BEX2 is a regulator of mitochondrial apoptosis and G1 cell cycle in breast cancer. It regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity. The homology between human BEX1 and BEX2 is 94%. This antibody detects both BEX1 and BEX2.

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