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BCR-Specific Polyclonal antibody

BCR-Specific Polyclonal Antibody for IF/ICC,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IF/ICC,ELISA

Conjugate

Unconjugated

Cat No : 19790-1-AP

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Synonyms

ALL, BCR, breakpoint cluster region, CML, D22S11, D22S662, PHL

验证数据展示

  • IF Staining of HeLa using 19790-1-AP

    IF Staining of HeLa using 19790-1-AP

    Immunofluorescent analysis of Hela cells, using BCR antibody 19790-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

产品信息

19790-1-AP targets BCR-Specific in IF, ELISA applications and shows reactivity with human samples.

Tested Applications IF/ICC,ELISA
Tested Reactivity human
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name breakpoint cluster region
Synonyms ALL, BCR, breakpoint cluster region, CML, D22S11, D22S662, PHL
Calculated Molecular Weight 143 kDa
GenBank Accession NumberNM_004327
Gene Symbol BCR
Gene ID (NCBI) 613
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP11274
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

BCR, also named as BCR1 and D22S11, is a GTPase-activating protein for RAC1 and CDC42. BCR promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. BCR displays serine/threonine kinase activity. BCR catalyzes the reaction: ATP + a protein = ADP + a phosphoprotein. A chromosomal aberration involving BCR is a cause of chronic myeloid leukemia (CML). The antibody is specific to BCR.