验证数据展示
Planning an IHC experiment? We recommend our IHCeasy BCR Ready-To-Use IHC Kit. BCR primary antibody included.
产品信息
19790-1-AP targets BCR-Specific in ELISA applications and shows reactivity with human samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | breakpoint cluster region |
| 别名 | BCR, Renal carcinoma antigen NY-REN-26, EC:2.7.11.1, breakpoint cluster region, BCR1 |
| 计算分子量 | 143 kDa |
| GenBank蛋白编号 | NM_004327 |
| 基因名称 | BCR |
| Gene ID (NCBI) | 613 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P11274 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
BCR, also named as BCR1 and D22S11, is a GTPase-activating protein for RAC1 and CDC42. BCR promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. BCR displays serine/threonine kinase activity. BCR catalyzes the reaction: ATP + a protein = ADP + a phosphoprotein. A chromosomal aberration involving BCR is a cause of chronic myeloid leukemia (CML). The antibody is specific to BCR.