验证数据展示
产品信息
33437-1-PBS targets BAZ2B in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag36147 Product name: Recombinant human BAZ2B protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1833-2080 aa of NM_013450.3 Sequence: DNPLDIAVTRLADLERNIERRIEEDIAPGLRVWRRALSEARSAAQVALCIQQLQKSIAWEKSIMKVYCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIAKASGQTLKIKKLHVKGKKTNESKKGKKVTLTGDTEDEDSASTSSSLKRGNKDLKKRKMEENTSINLSKQESFTSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKL 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | bromodomain adjacent to zinc finger domain, 2B |
| 别名 | KIAA1476, WALp4 |
| 计算分子量 | 240kDa，2168aa |
| 观测分子量 | 220-240 kDa |
| GenBank蛋白编号 | NM_013450.3 |
| 基因名称 | BAZ2B |
| Gene ID (NCBI) | 29994 |
| RRID | AB_3742971 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q9UIF8 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
BAZ2B(Bromodomain adjacent to zinc finger domain protein 2) is a regulatory subunit of the ATP-dependent chromatin remodeling complexes BRF1 and BRF5, which control access to DNA during DNA-templated processes. BAZ2B has been implicated in several diseases and also in unhealthy ageing. Loss of BAZ2B function has been postulated to cause neurodevelopmental disorders (PMID: 31999386, 31999386).
