验证数据展示
产品信息
67830-1-PBS targets BAD in WB, IF/ICC, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat samples.
经测试应用 | WB, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | Human, Mouse, Rat |
免疫原 | Peptide 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | BCL2-associated agonist of cell death |
别名 | BAD, BBC2, BBC6 |
计算分子量 | 18 kDa |
观测分子量 | 18-25 kDa |
GenBank蛋白编号 | BC001901 |
基因名称 | BAD |
Gene ID (NCBI) | 572 |
RRID | AB_2918592 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | Q92934 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
BAD, also named as BBC6 and BCL2L8, promotes cell death. It is successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. BAD can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. It appears to act as a link between growth factor receptor signaling and the apoptotic pathways.