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Species Reactivity
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Conjugate
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Conjugate
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验证数据展示

  • FC experiment of mouse peritoneal macrophages using 65221-1-Ig (same clone as 65221-1-PBS)

    FC experiment of mouse peritoneal macrophages using 65221-1-Ig (same clone as 65221-1-PBS)

    1X10^6 mouse peritoneal macrophages were surface stained with 1 ug Anti-Mouse CD276 (65221-1-Ig, Clone:MJ18) and FITC anti-rat IgG1 Antibody at dilution 1:100 (red), or unstained (blue). Cells were not fixed. This data was developed using the same antibody clone with 65221-1-PBS in a different storage buffer formulation.

Anti-Mouse B7-H3/CD276 (MJ18), PBS Only

B7-H3/CD276 Monoclonal Antibody for FC
Cat No. 65221-1-PBS

产品说明书

CloneNo. MJ18

宿主/亚型

Rat / IgG1, kappa

种属反应性

mouse

应用

FC

别名

Cd276, CD276 antigen, B7RP 2, B7-H3, B7h3

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

65221-1-PBS targets B7-H3/CD276 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原 Mouse IgG2a Fc-CD276 (aa 1-242) fusion protein 种属同源性预测
宿主/亚型 Rat / IgG1, kappa
抗体类别 Monoclonal
产品类型 Antibody
全称 CD276 antigen
别名 Cd276, CD276 antigen, B7RP 2, B7-H3, B7h3
GenBank蛋白编号BC019436
基因名称 Cd276
Gene ID (NCBI) 102657
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ8VE98
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD276 (also known as B7-H3) is a type I transmembrane protein expressed on many tissues and cell types. CD276 is a 100-kDa glycoprotein that belongs to the B7 immunoregulatory family and participates in the regulation of T-cell-mediated immune response probably by functioning as both a T cell costimulator and coinhibitor (PMID: 25567370; 20696859). Overexpressed on a wide range of human solid cancers, CD276 has been implicated in cancer progression and metastasis and becomes an attractive target for cancer immunotherapy (PMID: 27208063).