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验证数据展示

  • WB analysis using 21291-1-AP (same clone as 21291-1-PBS)

    WB analysis using 21291-1-AP (same clone as 21291-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 21291-1-AP (B3GNT6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21291-1-PBS in a different storage buffer formulation.

  • IHC staining of human stomach cancer using 21291-1-AP (same clone as 21291-1-PBS)

    IHC staining of human stomach cancer using 21291-1-AP (same clone as 21291-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 21291-1-AP (B3GNT6 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21291-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon cancer using 21291-1-AP (same clone as 21291-1-PBS)

    IHC staining of human colon cancer using 21291-1-AP (same clone as 21291-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 21291-1-AP (B3GNT6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21291-1-PBS in a different storage buffer formulation.

  • IHC staining of human colon cancer using 21291-1-AP (same clone as 21291-1-PBS)

    IHC staining of human colon cancer using 21291-1-AP (same clone as 21291-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 21291-1-AP (B3GNT6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21291-1-PBS in a different storage buffer formulation.

B3GNT6 Polyclonal antibody, PBS Only

B3GNT6 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 21291-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

BGnT-6, BGnT 6, Beta-1,3-N-acetylglucosaminyltransferase 6, B3Gn-T6, B3Gn T6

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

21291-1-PBS targets B3GNT6 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag15825

Product name: Recombinant human B3GNT6 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 102-343 aa of BC103910

Sequence: PLLWDAPAKCAGGRGVFLLLAVKSAPEHYERRELIRRTWGQERSYGGRPVRRLFLLGTPGPEDEARAERLAELVALEAREHGDVLQWAFADTFLNLTLKHLHLLDWLAARCPHARFLLSGDDDVFVHTANVVRFLQAQPPGRHLFSGQLMEGSVPIRDSWSKYFVPPQLFPGSAYPVYCSGGGFLLSGPTARALRAAARHTPLFPIDDAYMGMCLERAGLAPSGHEGIRPFGVQLPGAQQSS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
别名 BGnT-6, BGnT 6, Beta-1,3-N-acetylglucosaminyltransferase 6, B3Gn-T6, B3Gn T6
计算分子量 384 aa, 43 kDa
观测分子量 43 kDa
GenBank蛋白编号BC103910
基因名称 B3GNT6
Gene ID (NCBI) 192134
RRIDAB_2878834
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ6ZMB0
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The B3GNT6 protein, also known as core 3 synthase, is a member of the O-GlcNAc transferase (OGT) family and adds an N-acetylglucosamine to N-acetylgalactosamine-modifed serine or threonine. The B3GNT6 protein is responsible for the formation of the core 3 structure of O-glycans, which are important components of mucin-type glycoproteins. This process is known as the protein O-GlcNAcylation modifcation. B3GNT6 expression has been reported to be largely downregulated in gastric and colorectal cancers. B3GNT6 has 3 isoforms with the molecular mass of 29 and 43 kDa. (PMID: 35387659)

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