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验证数据展示

  • WB analysis using 23302-1-AP (same clone as 23302-1-PBS)

    WB analysis using 23302-1-AP (same clone as 23302-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 23302-1-AP (Angiopoietin 1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23302-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 23302-1-AP (same clone as 23302-1-PBS)

    IF Staining of HeLa using 23302-1-AP (same clone as 23302-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using Angiopoietin 1 antibody (23302-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 23302-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

Angiopoietin 1 Polyclonal antibody, PBS Only

Angiopoietin 1 Polyclonal Antibody for WB, IF/ICC, ELISA
Cat No. 23302-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IF/ICC, ELISA

别名

ANGPT1, AGP1, AGPT, ANG 1, ANG1

缓冲液配方: 
偶联物:  Unconjugated
规格价格库存

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产品信息

23302-1-PBS targets Angiopoietin 1 in applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IF/ICC, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag18829

Product name: Recombinant human ANGPT1 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 161-293 aa of BC152411

Sequence: IQLLENSLSTYKLEKQLLQQTNEILKIHEKNSLLEHKILEMEGKHKEELDTLKEEKENLQGLVTRQTYIIQELEKQLNRATTNNSVLQKQQLELMDTVHNLVNLCTKEGVLLKGGKREEEKPFRDCADVYQAG

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 angiopoietin 1
别名 ANGPT1, AGP1, AGPT, ANG 1, ANG1
计算分子量 498 aa, 58 kDa
观测分子量 70 kDa
GenBank蛋白编号BC152411
基因名称 Angiopoietin 1
Gene ID (NCBI) 284
RRIDAB_2879250
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ15389
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Angiopoietin 1 is a 70-kDa secreted glycoprotein generated from vascular mural cells, pericytes, and certain other cells. Angiopoietin 1 participates in vascular differentiation through angiogenesis, which is the process of the growth and remodelling of existing vessels. Angiopoietin 1 is also involved in the maintenance and turnover of blood vessels in mature animals. Angiopoietin 1 binds to and activates the TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation, playing an important role in the regulation of angiogenesis. Overexpression of Angiopoietin 1 has been proven to occur in malignant glioblastoma, neuroblastoma, non-small cell lung cancer, and other tumors.

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