Aurora B Polyclonal antibody

Aurora B Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

ELISA

Conjugate

Unconjugated

Cat No : 10792-1-AP

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Synonyms

AIK2, AIM 1, AIM1, ARK 2, ARK2, AurB, AURKB, Aurora B, aurora kinase B, Aurora related kinase 2, Aurora/IPL1 related kinase 2, IPL1, STK 1, STK12, STK5



发表文章中的应用

WBSee 1 publications below

产品信息

10792-1-AP targets Aurora B in ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications ELISA
Tested Reactivity human, mouse, rat
Immunogen Aurora B fusion protein Ag1246 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name aurora kinase B
Synonyms AIK2, AIM 1, AIM1, ARK 2, ARK2, AurB, AURKB, Aurora B, aurora kinase B, Aurora related kinase 2, Aurora/IPL1 related kinase 2, IPL1, STK 1, STK12, STK5
Calculated Molecular Weight39.2 kDa
GenBank Accession NumberBC013300
Gene Symbol AURKB
Gene ID (NCBI) 9212
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ96GD4
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Aurora B(AURKB) is also named as aurora kinase B, AIK2, AIM1, AIRK2, ARK2, STK1, STK12, STK5 and belongs to the Aurora subfamily. Aurora kinase B is a chromosomal passenger serine/threonine protein kinase that regulates accurate chromosomal segregation, cytokinesis, protein localization to the centromere and kinetochore, correct microtubule-kinetochore attachments, and regulation of the mitotic checkpoint(PMID:18311747). Expression levels of AURKB are increased in the anaplastic thyroid carcinoma cell lines ARO, Cal 62, and KAT-4(PMID:15562011).

发表文章

SpeciesApplicationTitle
WB

Exp Eye Res

Aurora kinase B disruption suppresses pathological retinal angiogenesis by affecting cell cycle progression

Authors - Weiye Zhu