ASCC1 Polyclonal antibody

ASCC1 Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

ELISA and More (1)

Conjugate

Unconjugated

Cat No : 12301-1-AP

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Synonyms

ASC 1 complex subunit p50, ASC1p50, ASCC1, CGI 18, RP11 150D20.4, Trip4 complex subunit p50



经过测试的应用

推荐稀释比

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

WBSee 3 publications below

产品信息

12301-1-AP targets ASCC1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications ELISA
Cited Applications WB
Tested Reactivity human, mouse, rat
Cited Reactivityhuman
Immunogen ASCC1 fusion protein Ag2946 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name activating signal cointegrator 1 complex subunit 1
Synonyms ASC 1 complex subunit p50, ASC1p50, ASCC1, CGI 18, RP11 150D20.4, Trip4 complex subunit p50
Calculated Molecular Weight 45.5 kDa
Observed Molecular Weight 45.5 kDa
GenBank Accession NumberBC012291
Gene Symbol ASCC1
Gene ID (NCBI) 51008
RRIDAB_2059350
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

ASCC1 (also known as p50) is a subunit of an uncharacterized complex, the activating signal co-integrator complex (ASCC). ASCC1 has been reported as regulator fo NF-kB pathway and potently inhibits the expression of NF-kB target genes. Mutations in ASCC1 in patients with Barrett esophagus (BE) have been identified as a risk factor of esophageal adenocarcinoma (EAC).

实验方案

Product Specific Protocols
WB protocol for ASCC1 antibody 12301-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Nat Commun

Extended DNA threading through a dual-engine motor module of the activating signal co-integrator 1 complex

Authors - Junqiao Jia
humanWB

Mol Cell

Translation stress and collided ribosomes are co-activators of cGAS.

Authors - Li Wan
humanWB

Mol Cell

Unresolved stalled ribosome complexes restrict cell-cycle progression after genotoxic stress.

Authors - Mark Stoneley