验证数据展示
经过测试的应用
| Positive WB detected in | SH-SY5Y cells, mouse brain tissue, mouse placenta tissue, mouse retina tissue, rat retina tissue, human placenta tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
84724-4-RR targets ARMC9 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 | ARMC9 fusion protein Ag27511 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | armadillo repeat containing 9 |
| 别名 | 242346G7 |
| 计算分子量 | 817 aa, 92 kDa |
| 观测分子量 | 75 kDa |
| GenBank蛋白编号 | BC004514 |
| 基因名称 | ARMC9 |
| Gene ID (NCBI) | 80210 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | Q7Z3E5 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
ARMC9 (Armadillo Repeat Containing 9) belongs to the ARMC subfamily characterized by a class of tandem repeat proteins with a length of approximately 42 amino acids (PMID: 34912852). ARMC9 localizes to centrioles and the proximal portion of the cilium in mammalian cilia (PMID: 32453716). The variants of ARMC9 lead to Joubert syndrome (JBTS), a recessive neurodevelopmental ciliopathy characterized by characterized by hypotonia, ataxia, abnormal eye movements, and variable cognitive impairment(PMID: 28625504; PMID: 32453716). ARMC9 has two isoforms with molecular weights of 92 kDa and 76 kDa.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for ARMC9 antibody 84724-4-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |