验证数据展示
产品信息
82966-2-PBS targets ARHGEF19 in IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | IF/ICC, FC (Intra), Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag11645 Product name: Recombinant human ARHGEF19 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 454-802 aa of BC040640 Sequence: VVLDHCPAFRRVYLPYVTNQAYQERTYQRLLLENPRFPGILARLEESPVCQRLPLTSFLILPFQRITRLKMLVENILKRTAQGSEDEDMATKAFNALKELVQECNASVQSMKRTEELIHLSKKIHFEGKIFPLISQARWLVRHGELVELAPLPAAPPAKLKLSSKAVYLHLFNDCLLLSRRKELGKFAVFVHAKMAELQVRDLSLKLQGIPGHVFLLQLLHGQHMKHQFLLRARTESEKQRWISALCPSSPQEDKEVISEGEDCPQVQCVRTYKALHPDELTLEKTDILSVRTWTSDGWLEGVRLADGEKGWVPQAYVEEISSLSARLRNLRENKRVTSATSKLGEAPV 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | Rho guanine nucleotide exchange factor (GEF) 19 |
| 别名 | 230290F5, Ephexin-2, WGEF |
| 计算分子量 | 802 aa, 89 kDa |
| GenBank蛋白编号 | BC040640 |
| 基因名称 | ARHGEF19 |
| Gene ID (NCBI) | 128272 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q8IW93 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Rho guanine nucleotide exchange factors (RHOGEFs) are proteins that could regulate Rho GTPases, which can be involved in a variety of physiological processes, such as survival, development, differentiation, and motility. ARHGEF19 also known as WGEF, is a member of the RhoGEF family. ARHGEF19 contains two identical functional domains, including the Dbl homology (DH) and pleckstrin homology (PH) domain(PMID:32993957). ARHGEF19 was highly expressed in human breast cancer(PMID: 34813497).
