验证数据展示
Planning an IHC experiment? We recommend our IHCeasy ARHGAP5 Ready-To-Use IHC Kit. ARHGAP5 primary antibody included.
产品信息
55165-1-PBS targets ARHGAP5 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | Rho GTPase activating protein 5 |
| 别名 | GFI2, p190 B, p190-B, Rho GTPase-activating protein 5, RhoGAP5 |
| 计算分子量 | 172 kDa |
| 观测分子量 | 170-190 kDa |
| GenBank蛋白编号 | NM_001173 |
| 基因名称 | ARHGAP5 |
| Gene ID (NCBI) | 394 |
| RRID | AB_10858787 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q13017 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
ARHGAP5, also named as RHOGAP5 and p190-B, is GTPase-activating protein for Rho family members. It may play a role in the reduction of the p21rasGTPase-activating potential of p120GAP. ARHGAP5 can be directly phosphorylated on a single identified tyrosine residue by the activated INS and IGF-1 receptors. It also has been shown to be tyrosine phosphorylated by cSrc and vSrc. Additionally the GAP domain of ARHGAP5 is shown to attenuate signal transducing activity of Rac, Rho and CDC42. The antibody is specific to ARHGAP5.
