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验证数据展示

  • WB analysis of mouse heart using 55139-1-AP (same clone as 55139-1-PBS)

    WB analysis of mouse heart using 55139-1-AP (same clone as 55139-1-PBS)

    mouse heart tissue were subjected to SDS PAGE followed by western blot with 55139-1-AP (ARHGAP10 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.

  • IHC staining of human heart using 55139-1-AP (same clone as 55139-1-PBS)

    IHC staining of human heart using 55139-1-AP (same clone as 55139-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 55139-1-AP (ARHGAP10 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.

  • IHC staining of human heart using 55139-1-AP (same clone as 55139-1-PBS)

    IHC staining of human heart using 55139-1-AP (same clone as 55139-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 55139-1-AP (ARHGAP10 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 55139-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

ARHGAP10 Polyclonal antibody, PBS Only

ARHGAP10 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 55139-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

55139-1-PBS targets ARHGAP10 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 Rho GTPase activating protein 10
别名
计算分子量 89 kDa
观测分子量 89 kDa
GenBank蛋白编号NM_024605
基因名称 ARHGAP10
Gene ID (NCBI) 79658
RRIDAB_10794449
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDA1A4S6
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ARHGAP10, also named as GRAF2, is GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. It is essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. ARHGAP10 inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. It stabilizes PAK-2p34 thereby increasing stimulation of cell death. The antibody is specific to ARHGAP10.

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