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验证数据展示

  • WB analysis using 66550-1-Ig (same clone as 66550-1-PBS)

    WB analysis using 66550-1-Ig (same clone as 66550-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66550-1-Ig (ARC antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66550-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 66550-1-Ig (same clone as 66550-1-PBS)

    IHC staining of mouse brain using 66550-1-Ig (same clone as 66550-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 66550-1-Ig (ARC antibody) at dilution of 1:2000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66550-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with ARC antibody included
  • IF Staining of SH-SY5Y using 66550-1-Ig (same clone as 66550-1-PBS)

    IF Staining of SH-SY5Y using 66550-1-Ig (same clone as 66550-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed SH-SY5Y cells using ARC antibody (66550-1-Ig, Clone: 1G4B5 ) at dilution of 1:800 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L), CL594-Phalloidin (red). This data was developed using the same antibody clone with 66550-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

ARC Monoclonal antibody, PBS Only

ARC Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 66550-1-PBS

产品说明书

CloneNo. 1G4B5

宿主/亚型

Mouse / IgG1

种属反应性

human, mouse, rat, pig, rabbit

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

hArc, Arg3.1, ARC/ARG3.1, Activity-regulated gene 3.1 protein homolog, Activity-regulated cytoskeleton-associated protein

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy ARC Ready-To-Use IHC Kit. ARC primary antibody included.

产品信息

66550-1-PBS targets ARC in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig, rabbit samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat, pig, rabbit
免疫原 ARC fusion protein Ag9445 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 activity-regulated cytoskeleton-associated protein
别名 hArc, Arg3.1, ARC/ARG3.1, Activity-regulated gene 3.1 protein homolog, Activity-regulated cytoskeleton-associated protein
计算分子量 396 aa, 45 kDa
观测分子量 50 kDa
GenBank蛋白编号BC012321
基因名称 ARC
Gene ID (NCBI) 23237
RRIDAB_2881912
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDQ7LC44
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ARC, also named as KIAA0278 and Arg3.1, mediates endocytosis of neuronal AMPA-type glutamate receptors (AMPARs). It is required for consolidation of synaptic plasticity as well as formation of long-term memory. ARC plays a role in the regulation of cell morphology and cytoskeletal organization. It is required in the stress fiber dynamics and cell migration. Recent study shows that expression of Arc can regulate cognitive flexibility.