- Featured Product
- KD/KO Validated
APOBEC3C Polyclonal antibody
APOBEC3C Polyclonal Antibody for IHC, WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human and More (1)
Applications
IHC, WB, ELISA and More (1)
Conjugate
Unconjugated
验证数据展示
经过测试的应用
| Positive WB detected in | Caco-2 cells, HEK-293 cells, K-562 cells, SW480 cells |
| Positive IHC detected in | human ovary tumor tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| Immunohistochemistry (IHC) | IHC : 1:100-1:400 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
10591-1-AP targets APOBEC3C in WB, IF, IHC, ELISA applications and shows reactivity with human samples.
| Tested Applications | IHC, WB, ELISA |
| Cited Applications | WB, IF, IHC |
| Tested Reactivity | human |
| Cited Reactivity | human, mouse |
| Immunogen | APOBEC3C fusion protein Ag0886 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| Synonyms | APOBEC1 like, APOBEC1L, APOBEC3, APOBEC3C, ARDC2, ARDC4, ARP5, bK150C2.3, PBI, Phorbolin I |
| Calculated Molecular Weight | 23 kDa |
| Observed Molecular Weight | 23 kDa |
| GenBank Accession Number | BC011739 |
| Gene Symbol | APOBEC3C |
| Gene ID (NCBI) | 27350 |
| RRID | AB_2057393 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9NRW3 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
APOBEC3C(apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C) is also named as APOBEC1L, PBI and belongs to the cytidine and deoxycytidylate deaminase family.APOBEC3C is related to APOBEC1, a cytidine deaminase responsible for cytidine-to-uridine editing of apolipoprotein B (APOB)mRNA.It can form a dimer(PMID:19074429).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for APOBEC3C antibody 10591-1-AP | Download protocol |
| IHC protocol for APOBEC3C antibody 10591-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Nucleic Acids Res Enterovirus 71 antagonizes the inhibition of the host intrinsic antiviral factor A3G. | ||
Oncogenesis Aberrant APOBEC3C expression induces characteristic genomic instability in pancreatic ductal adenocarcinoma. | ||
Sci Rep Expression and subcellular localisation of AID and APOBEC3 in adenoid and palatine tonsils. | ||
J Virol Infection of Bronchial Epithelial Cells by the Human Adenoviruses A12, B3, and C2 Differently Regulates the Innate Antiviral Effector APOBEC3B. | ||
Retrovirology Natural APOBEC3C variants can elicit differential HIV-1 restriction activity. |
