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APLP2 Recombinant monoclonal antibody

APLP2 Uni-rAb® Recombinant Antibody for WB, IF/ICC, ELISA
Cat No. 84703-3-RR

产品说明书

CloneNo. 241655G7

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IF/ICC, ELISA

241655G7, A4, Amyloid beta, Amyloid beta precursor like protein 2, Amyloid like protein 2

缓冲液配方:  PBS and Azide
PBS and Azide
PBS Only
偶联物:  Unconjugated
Unconjugated
规格价格库存


经过测试的应用

Positive WB detected inrat brain tissue, mouse brain tissue, SH-SY5Y cells, HEK-293 cells
Positive IF/ICC detected inSH-SY5Y cells
Planning an IHC experiment? We recommend our IHCeasy APLP2 Ready-To-Use IHC Kit. APLP2 primary antibody included.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
Immunofluorescence (IF)/ICCIF/ICC : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

84703-3-RR targets APLP2 in WB, IF/ICC, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IF/ICC, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag6842

Product name: Recombinant human APLP2 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 33-360 aa of BC000373

Sequence: YIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDKKQCKSRFVTPFKCLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWHTVVKEACLTQGMTLYSYGMLLPCGVDQFHGTEYVCCPQTKIIGSVSKEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 amyloid beta (A4) precursor-like protein 2
别名 241655G7, A4, Amyloid beta, Amyloid beta precursor like protein 2, Amyloid like protein 2
计算分子量 87 kDa
观测分子量95-120 kDa
GenBank蛋白编号BC000373
基因名称 APLP2
Gene ID (NCBI) 334
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDQ06481
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Amyloid precursor-like protein-2 (APLP2) is a member of the APP (amyloid precursor protein) family including APP, APLP1, and APLP2. APLP2 is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. APLP2 has been shown to regulate multiple cellular functions such as neurite outgrowth, axogenesis, corneal epithelial wound healing, cell adhesion, migration, and mitosis. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. APLP2 has been implicated in the pathogenesis of Alzheimer's disease.

实验方案

Product Specific Protocols
WB protocol for APLP2 antibody 84703-3-RRDownload protocol
IF protocol for APLP2 antibody 84703-3-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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