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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 84703-3-RR (same clone as 84703-3-PBS)

    WB analysis using 84703-3-RR (same clone as 84703-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84703-3-RR (APLP2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84703-3-PBS in a different storage buffer formulation.

  • IF Staining of SH-SY5Y using 84703-3-RR (same clone as 84703-3-PBS)

    IF Staining of SH-SY5Y using 84703-3-RR (same clone as 84703-3-PBS)

    Immunofluorescent analysis of (4% PFA) fixed SH-SY5Y cells using APLP2 antibody (84703-3-RR, Clone: 241655G7 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84703-3-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84703-3-RR

    Affinity and Kinetic Characterization of 84703-3-RR

    Biolayer interferometry (BLl) kinetic assays of 84703-3-RR against Human APLP2 were performed. The affinity constant is 0.675 nM.

    {{ptg:ProductFeaturesInfo}}

APLP2 Recombinant monoclonal antibody, PBS Only

APLP2 Uni-rAb® Recombinant Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 84703-3-PBS

产品说明书

CloneNo. 241655G7

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IF/ICC, Indirect ELISA

别名

241655G7, A4, Amyloid beta, Amyloid beta precursor like protein 2, Amyloid like protein 2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy APLP2 Ready-To-Use IHC Kit. APLP2 primary antibody included.

产品信息

84703-3-PBS targets APLP2 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag6842

Product name: Recombinant human APLP2 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 33-360 aa of BC000373

Sequence: YIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDKKQCKSRFVTPFKCLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWHTVVKEACLTQGMTLYSYGMLLPCGVDQFHGTEYVCCPQTKIIGSVSKEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 amyloid beta (A4) precursor-like protein 2
别名 241655G7, A4, Amyloid beta, Amyloid beta precursor like protein 2, Amyloid like protein 2
计算分子量 87 kDa
观测分子量95-120 kDa
GenBank蛋白编号BC000373
基因名称 APLP2
Gene ID (NCBI) 334
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDQ06481
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Amyloid precursor-like protein-2 (APLP2) is a member of the APP (amyloid precursor protein) family including APP, APLP1, and APLP2. APLP2 is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. APLP2 has been shown to regulate multiple cellular functions such as neurite outgrowth, axogenesis, corneal epithelial wound healing, cell adhesion, migration, and mitosis. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. APLP2 has been implicated in the pathogenesis of Alzheimer's disease.