验证数据展示
产品信息
19533-1-AP targets ANKRD28-phospho1040S/1044S in ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | ankyrin repeat domain 28 |
| 别名 | ANKRD28, ankyrin repeat domain 28, KIAA0379, PITK |
| 计算分子量 | 117 kDa |
| GenBank蛋白编号 | NM_015199 |
| 基因名称 | ANKRD28 |
| Gene ID (NCBI) | 23243 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | O15084 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
ANKRD28, also named as KIAA0379 and PITK, putative to be a regulatory subunit of protein phospatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. ANKRD28 involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. ANKRD28 Targets PPP1C to modulate HNRPK phosphorylation. The antibody is to phopho-Ser1040 and Ser1044.
