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验证数据展示

  • IHC staining of mouse liver using 24087-1-AP (same clone as 24087-1-PBS)

    IHC staining of mouse liver using 24087-1-AP (same clone as 24087-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 24087-1-AP (ANKRD18A antibody) at dilution of 1:600 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24087-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 24087-1-AP (same clone as 24087-1-PBS)

    IHC staining of mouse brain using 24087-1-AP (same clone as 24087-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 24087-1-AP (ANKRD18A antibody) at dilution of 1:600 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24087-1-PBS in a different storage buffer formulation.

ANKRD18A Polyclonal antibody, PBS Only

ANKRD18A Polyclonal Antibody for IHC, Indirect ELISA
Cat No. 24087-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, Indirect ELISA

别名

ankyrin repeat domain 18A, KIAA2015

缓冲液配方:  PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

24087-1-PBS targets ANKRD18A in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag21335

Product name: Recombinant human ANKRD18A protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 262-390 aa of BC152434

Sequence: NHLRNDNQETAAMKPANLKKRKERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQ

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 ankyrin repeat domain 18A
别名 ankyrin repeat domain 18A, KIAA2015
计算分子量 992 aa, 116 kDa
GenBank蛋白编号BC152434
基因名称 ANKRD18A
Gene ID (NCBI) 253650
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen Affinity purified
UNIPROT IDQ8IVF6
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ANKRD18A is an ankyrin repeat-containing protein that likely operates in the realm of epigenetic regulation, potentially influencing gene expression via DNA methylation mechanisms. Although its exact biochemical roles remain unclear, its frequent promoter hypermethylation in lung cancer, along with germline variation in vulvar skin disorders, underscores a compelling link to disease pathogenesis. Located on chromosome 9p13.1, ANKRD18A remains a compelling subject for further functional and clinical exploration.

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