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验证数据展示

  • WB analysis using 86193-1-RR (same clone as 86193-1-PBS)

    WB analysis using 86193-1-RR (same clone as 86193-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86193-1-RR (ANGPTL3 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86193-1-PBS in a different storage buffer formulation.

  • Sample test of MP02294-1

    Sample test of MP02294-1

    The mean ANGPTL3 concentration was determined to be 14.8 ng/mL in human serum.

  • Cytometric bead array standard curve of MP02294-1

    Cytometric bead array standard curve of MP02294-1

    Cytometric bead array standard curve of MP02294-1, ANGPTL3 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 86193-2-PBS. Detection antibody: 86193-1-PBS. Standard: Ag2573. Range: 1.563-200 ng/mL.

ANGPTL3 Recombinant antibody, PBS Only (Detector)

ANGPTL3 Uni-rAbTM Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA, Sample test
Cat No. 86193-1-PBS

产品说明书

CloneNo. 250808F7

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, Cytometric bead array, Indirect ELISA, Sample test

别名

ANG-5, Angiopoietin like protein 3, Angiopoietin related protein 3, Angiopoietin-5, Angiopoietin-like protein 3

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

86193-1-PBS targets ANGPTL3 as part of a matched antibody pair:

MP02294-1: 86193-2-PBS capture and 86193-1-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 WB, Cytometric bead array, Indirect ELISA, Sample test Application Description
经测试反应性 human, mouse, rat
免疫原 ANGPTL3 fusion protein Ag2573 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 angiopoietin-like 3
别名 ANG-5, Angiopoietin like protein 3, Angiopoietin related protein 3, Angiopoietin-5, Angiopoietin-like protein 3
计算分子量 460 aa, 54 kDa
观测分子量54 kDa
GenBank蛋白编号BC058287
基因名称 ANGPTL3
Gene ID (NCBI) 27329
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ9Y5C1
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ANGPTL3 belongs to the angiopoietin-like protein family. ANGPTL3 is mainly synthesized by liver cells and is notably expressed in kidney podocytes. Accumulating evidences have revealed that ANGPTL3 plays a critical role in both biological processes, such as lipid metabolism, angiogenesis and haematopoietic function and pathological changes, including atherosclerosis, carcinogenesis, nephrotic syndrome, diabetes, liver diseases and so on. Thus, ANGPTL3 may serve as a potential biomarker in these diseases.