验证数据展示
经过测试的应用
| Positive WB detected in | HeLa cells, Jurkat cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
30517-1-AP targets AK6 in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | AK6 fusion protein Ag29330 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | AK6 |
| 别名 | Adenylate kinase isoenzyme 6, CINAP, KAD6 |
| 计算分子量 | 20 kDa |
| 观测分子量 | 20-24 kDa |
| GenBank蛋白编号 | NM_016283.4 |
| 基因名称 | AK6 |
| Gene ID (NCBI) | 102157402 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9Y3D8 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Adenylate Kinase 6 (AK6), also known as human coilin-interacting nuclear ATPase protein (hCINAP), is a unique enzyme that belongs to the adenylate kinase family. It is encoded by the AK6 gene located on chromosome 5q13.2. AK6 is a dual-activity enzyme, possessing both adenylate kinase and ATPase activities. The protein is involved in various biological processes, including gene transcription, ribosome quality control, embryonic development, cellular senescence, metabolism, proliferation, apoptosis, DNA damage response, and inflammation. It is also implicated in tumor development and has been explored as a potential drug target for cancer and neurodegenerative diseases.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for AK6 antibody 30517-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |