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AGGF1 Polyclonal antibody

AGGF1 Polyclonal Antibody for WB, ELISA
Cat No. 11889-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat and More (3)

应用

WB, ELISA and More (3)

HUS84971, HSU84971, GPATCH7, GPATC7, G patch domain-containing protein 7

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inHUVEC cells, HeLa cells, L02 cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:8000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

11889-1-AP targets AGGF1 in WB, IHC, IF, IP, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, ELISA Application Description
文献引用应用WB, IHC, IF, IP
经测试反应性 human, mouse, rat
文献引用反应性human, mouse, rat, zebrafish, macaque, rhesus
免疫原 AGGF1 fusion protein Ag2497 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 angiogenic factor with G patch and FHA domains 1
别名 HUS84971, HSU84971, GPATCH7, GPATC7, G patch domain-containing protein 7
计算分子量 714 aa, 81 kDa
观测分子量 84-100 kDa
GenBank蛋白编号BC029382
基因名称 AGGF1
Gene ID (NCBI) 55109
RRIDAB_2305338
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ8N302
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

The angiogenic factor gene, AGGF1 (or VG5Q), is identified as a candidate susceptibility gene for Klippel-Trenaunay syndrome (KTS) which is a severe congenital disorder characterized by capillary malformations, venous malformations or varicose veins, and hypertrophy of the affected tissues. AGGF1 protein can bind to endothelial cells and promote cell proliferation. AGGF1 shows strong expression in blood vessels and is secreted as vessel formation is initiated. Regulation of AGGF1 by GATA1 may play roles in endothelial cell biology and angiogenesis.

实验方案

Product Specific Protocols
WB protocol for AGGF1 antibody 11889-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB,IHC

Nat Commun

A non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and heart failure.

Authors - Yufeng Yao
mouseWB

Mol Ther

The 3' Untranslated Region Protects the Heart from Angiotensin II-Induced Cardiac Dysfunction via AGGF1 Expression.

Authors - Lexi Ding
mouseWB

PLoS Biol

Angiogenic Factor AGGF1 Activates Autophagy with an Essential Role in Therapeutic Angiogenesis for Heart Disease.

Authors - Qiulun Lu
  • KO Validated
ratWB,IF

Arterioscler. Thromb. Vasc. Biol.

Angiogenic Factor With G Patch and FHA Domains 1 Is a Novel Regulator of Vascular Injury.

Authors - Bisheng Zhou
  • KD Validated
humanWB

Mol Ther Nucleic Acids

circ-SHKBP1 Regulates the Angiogenesis of U87 Glioma-Exposed Endothelial Cells through miR-544a/FOXP1 and miR-379/FOXP2 Pathways.

Authors - Qianru He

FASEB J

Angiotensin II increases angiogenesis by NF-κB-mediated transcriptional activation of angiogenic factor AGGF1.

Authors - Wenxia Si
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