验证数据展示
产品信息
23494-1-AP targets ADAM18 in ELISA applications and shows reactivity with human samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag18672 Product name: Recombinant human ADAM18 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 338-687 aa of BC121045 Sequence: LRATCIMNHEAVSASGRKIFSNCSMHDYRYFVSKFETKCLQKLSNLQPLHQNQPVCGNGILESNEECDCGNKNECQFKKCCDYNTCKLKGSVKCGSGPCCTSKCELSIAGTPCRKSIDPECDFTEYCNGTSSNCVPDTYALNGRLCKLGTAYCYNGQCQTTDNQCAKIFGKGAQGAPFACFKEVNSLHERSENCGFKNSQPLPCERKDVLCGKLACVQPHKNANKSDAQSTVYSYIQDHVCVSIATGSSMRSDGTDNAYVADGTMCGPEMYCVNKTCRKVHLMGYNCNATTKCKGKGICNNFGNCQCFPGHRPPDCKFQFGSPGGSIDDGNFQKSGDFYTEKGYNTHWNN 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | ADAM metallopeptidase domain 18 |
| 别名 | ADAM 18, ADAM18, ADAM27, tMDC III, TMDC3, tMDCIII |
| 计算分子量 | 739 aa, 83 kDa |
| GenBank蛋白编号 | BC121045 |
| 基因名称 | ADAM18 |
| Gene ID (NCBI) | 8749 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9Y3Q7 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
ADAM18(Disintegrin and metalloproteinase domain-containing protein 18) is also named as TMDC3. It is a sperm surface membrane protein that may be involved in spermatogenesis and fertilization. This is a non catalytic metalloprotease-like protein. It has a tripeptide motif (ECD) within disintegrin-like domain, which could be involved in the binding to egg integrin receptor and thus could mediate sperm/egg binding. The fuli length protein has 12 glycosylation sites, a signal peptide and a propeptide.
