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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 81656-1-RR (same clone as 81656-1-PBS)

    WB analysis using 81656-1-RR (same clone as 81656-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 81656-1-RR (ACC1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 81656-1-PBS in a different storage buffer formulation.

  • IP experiment of HepG2 using 81656-1-RR (same clone as 81656-1-PBS)

    IP experiment of HepG2 using 81656-1-RR (same clone as 81656-1-PBS)

    IP result of anti-ACC1 (IP:81656-1-RR, 4ug; Detection:81656-1-RR 1:2000) with HepG2 cells lysate 1640 ug. This data was developed using the same antibody clone with 81656-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 81656-1-RR

    Affinity and Kinetic Characterization of 81656-1-RR

    Biolayer interferometry (BLl) kinetic assays of 81656-1-RR against Human ACC1 were performed. The affinity constant is 2.28 nM.

ACC1 Recombinant antibody, PBS Only

ACC1 Uni-rAbTM Recombinant Antibody for WB, IP, Indirect ELISA
Cat No. 81656-1-PBS

产品说明书

CloneNo. 2I13

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IP, Indirect ELISA

别名

ACACA, ACC-alpha, ACCA, ACC, ACAC

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

81656-1-PBS targets ACC1 in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IP, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 ACC1 fusion protein Ag16452 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 acetyl-Coenzyme A carboxylase alpha
别名 ACACA, ACC-alpha, ACCA, ACC, ACAC
计算分子量 2383 aa, 275 kDa
观测分子量 250 kDa
GenBank蛋白编号BC137287
基因名称 Acetyl-CoA Carboxylase 1
Gene ID (NCBI) 31
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ13085
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ACACA(Acetyl-CoA carboxylase 1, ACC), also named as ACAC, ACC1 and ACCA, belongs to the biotin containing enzyme family. It catalyzes the synthesis of malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. ACACA is involved in the biosynthesis of fatty acids, and malonyl-CoA produced is used as a building block to extend the chain length of fatty acids by fatty acid synthase (FAS)(PMID:19900410). It has 4 isoforms produced by alternative promoter usage with the molecular weight between 260 kDa and 270 kDa.