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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 81656-1-RR (same clone as 81656-1-PBS)

    WB analysis using 81656-1-RR (same clone as 81656-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 81656-1-RR (ACC1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 81656-1-PBS in a different storage buffer formulation.

  • IP experiment of HepG2 using 81656-1-RR (same clone as 81656-1-PBS)

    IP experiment of HepG2 using 81656-1-RR (same clone as 81656-1-PBS)

    IP result of anti-ACC1 (IP:81656-1-RR, 4ug; Detection:81656-1-RR 1:2000) with HepG2 cells lysate 1640 ug. This data was developed using the same antibody clone with 81656-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 81656-1-RR

    Affinity and Kinetic Characterization of 81656-1-RR

    Biolayer interferometry (BLl) kinetic assays of 81656-1-RR against Human ACC1 were performed. The affinity constant is 2.28 nM.

    {{ptg:ProductFeaturesInfo}}

ACC1 Recombinant monoclonal antibody, PBS Only

ACC1 Uni-rAb® Recombinant Antibody for WB, IP, Indirect ELISA
Cat No. 81656-1-PBS

产品说明书

CloneNo. 2I13

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IP, Indirect ELISA

别名

ACACA, ACC-alpha, ACCA, ACC, ACAC

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

81656-1-PBS targets ACC1 in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IP, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag16452

Product name: Recombinant human ACC protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 2260-2383 aa of BC137287

Sequence: LLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLAEWLEKQLTEEDGVHSVIEENIKCISRDYVLKQIRSLVQANPEVAMDSIIHMTQHISPTQRAEVIRILSTMDSPST

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 acetyl-Coenzyme A carboxylase alpha
别名 ACACA, ACC-alpha, ACCA, ACC, ACAC
计算分子量 2383 aa, 275 kDa
观测分子量 250 kDa
GenBank蛋白编号BC137287
基因名称 Acetyl-CoA Carboxylase 1
Gene ID (NCBI) 31
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ13085
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ACACA(Acetyl-CoA carboxylase 1, ACC), also named as ACAC, ACC1 and ACCA, belongs to the biotin containing enzyme family. It catalyzes the synthesis of malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. ACACA is involved in the biosynthesis of fatty acids, and malonyl-CoA produced is used as a building block to extend the chain length of fatty acids by fatty acid synthase (FAS)(PMID:19900410). It has 4 isoforms produced by alternative promoter usage with the molecular weight between 260 kDa and 270 kDa.