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验证数据展示

  • WB analysis using 87969-1-RR (same clone as 87969-1-PBS)

    WB analysis using 87969-1-RR (same clone as 87969-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 87969-1-RR (ACAA1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 87969-1-PBS in a different storage buffer formulation.

  • WB analysis using 87969-1-RR (same clone as 87969-1-PBS)

    WB analysis using 87969-1-RR (same clone as 87969-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 87969-1-RR (ACAA1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 87969-1-PBS in a different storage buffer formulation.

  • WB analysis using 87969-1-RR (same clone as 87969-1-PBS)

    WB analysis using 87969-1-RR (same clone as 87969-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 87969-1-RR (ACAA1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 87969-1-PBS in a different storage buffer formulation.

ACAA1 Recombinant monoclonal antibody, PBS Only

ACAA1 Uni-rAb® Recombinant Antibody for WB, Indirect ELISA
Cat No. 87969-1-PBS

产品说明书

CloneNo. 260194F9

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, Indirect ELISA

别名

3 ketoacyl CoA thiolase, peroxisomal, 3-ketoacyl-CoA thiolase, peroxisomal, ACAA, Acetyl CoA acyltransferase, Acetyl-CoA acyltransferase

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy ACAA1 Ready-To-Use IHC Kit. ACAA1 primary antibody included.

产品信息

87969-1-PBS targets ACAA1 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag2972

Product name: Recombinant human ACAA1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 117-424 aa of BC011977

Sequence: STVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFEYPGN

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 acetyl-Coenzyme A acyltransferase 1
别名 3 ketoacyl CoA thiolase, peroxisomal, 3-ketoacyl-CoA thiolase, peroxisomal, ACAA, Acetyl CoA acyltransferase, Acetyl-CoA acyltransferase
计算分子量 424 aa, 44 kDa
观测分子量41 kDa
GenBank蛋白编号BC011977
基因名称 ACAA1
Gene ID (NCBI) 30
RRIDAB_3745839
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP09110
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ACAA1 (acetyl-CoA acyltransferase 1) is an enzyme involved in lipid β-oxidation and provides substrates to the tricarboxylic acid (TCA) cycle, a critical step in cellular metabolism (PMID:33194642). ACAA1 is also a biomarker in type 2 diabetes (T2D), predicting the pre-diabetic metabolic signature in mouse models (PMID:25784953). Moreover, ACAA1 is highly expressed in TNBC, serving as a potential therapeutic target in ACAA1-high tumors and a predictive biomarker of resistance to CDK4/6 inhibitors for RB1-proficient patients (PMID:37129951).

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