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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 84011-6-RR (same clone as 84011-6-PBS)

    WB analysis using 84011-6-RR (same clone as 84011-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84011-6-RR (ABR antibody) at dilution of 1:12000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84011-6-PBS in a different storage buffer formulation.

  • WB analysis using 84011-6-RR (same clone as 84011-6-PBS)

    WB analysis using 84011-6-RR (same clone as 84011-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84011-6-RR (ABR antibody) at dilution of 1:12000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84011-6-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84011-6-RR

    Affinity and Kinetic Characterization of 84011-6-RR

    Biolayer interferometry (BLl) kinetic assays of 84011-6-RR against Human ABR were performed. The affinity constant is 4.96 nM.

ABR Recombinant antibody, PBS Only

ABR Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 84011-6-PBS

产品说明书

CloneNo. 241121G1

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, Indirect ELISA

别名

MDB, active BCR related gene, 241121G1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

84011-6-PBS targets ABR in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 ABR fusion protein Ag29522 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 active BCR-related gene
别名 MDB, active BCR related gene, 241121G1
计算分子量 98 kDa
观测分子量97-100 kDa
GenBank蛋白编号NM_021962
基因名称 ABR
Gene ID (NCBI) 29
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ12979
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ABR (Active breakpoint cluster region-related protein) is the only protein known in humans and mice to share high homology with BCR (68% amino acid identity). BCR(Breakpoint cluster region) gene was originally identified due to its involvement in a specific chromosomal translocation that causes the development of chronic myeloid leukemia and a subset of acute lymphoblastic leukemia. The C-terminus is a GTPase-activating protein domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42. (PMID: 17116687, PMID: 37507586)