• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 84011-6-RR (same clone as 84011-6-PBS)

    WB analysis using 84011-6-RR (same clone as 84011-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84011-6-RR (ABR antibody) at dilution of 1:12000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84011-6-PBS in a different storage buffer formulation.

  • WB analysis using 84011-6-RR (same clone as 84011-6-PBS)

    WB analysis using 84011-6-RR (same clone as 84011-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84011-6-RR (ABR antibody) at dilution of 1:12000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84011-6-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84011-6-RR

    Affinity and Kinetic Characterization of 84011-6-RR

    Biolayer interferometry (BLl) kinetic assays of 84011-6-RR against Human ABR were performed. The affinity constant is 4.96 nM.

    {{ptg:ProductFeaturesInfo}}

ABR Recombinant monoclonal antibody, PBS Only

ABR Uni-rAb® Recombinant Antibody for WB, Indirect ELISA
Cat No. 84011-6-PBS

产品说明书

CloneNo. 241121G1

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, Indirect ELISA

别名

MDB, active BCR related gene, 241121G1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

84011-6-PBS targets ABR in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag29522

Product name: Recombinant human ABR protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-87 aa of NM_021962

Sequence: MEPLSHRGLPRLSWIDTLYSNFSYGTDEYDGEGNEEQKGPPEGSETMPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGK

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 active BCR-related gene
别名 MDB, active BCR related gene, 241121G1
计算分子量 98 kDa
观测分子量97-100 kDa
GenBank蛋白编号NM_021962
基因名称 ABR
Gene ID (NCBI) 29
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDQ12979
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

ABR (Active breakpoint cluster region-related protein) is the only protein known in humans and mice to share high homology with BCR (68% amino acid identity). BCR(Breakpoint cluster region) gene was originally identified due to its involvement in a specific chromosomal translocation that causes the development of chronic myeloid leukemia and a subset of acute lymphoblastic leukemia. The C-terminus is a GTPase-activating protein domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42. (PMID: 17116687, PMID: 37507586)