验证数据展示
产品信息
60153-1-PBS targets ABCD1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IF/ICC, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | ABCD1 fusion protein Ag12757 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | ATP-binding cassette, sub-family D (ALD), member 1 |
别名 | ABC42, ABCD1, Adrenoleukodystrophy protein, ALD, ALDP, AMN |
计算分子量 | 745 aa, 83 kDa |
观测分子量 | 75 kDa |
GenBank蛋白编号 | BC025358 |
基因名称 | ABCD1 |
Gene ID (NCBI) | 215 |
RRID | AB_10640436 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P33897 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
ABCD1 (also known as ALDP) is a member of the ATP-binding cassette (ABC) transporter superfamily which functions as transporter for a wide variety of substrates. It localizes to the peroxisomal membrane. The exact function is not clear so far. Various mutations of ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), an inherited neurodegenerative disease affecting the nervous system white matter and adrenal cortex.