验证数据展示
经过测试的应用
| Positive WB detected in | HEK-293 cells, HeLa cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
19764-1-AP targets ABCA13 in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | ATP-binding cassette, sub-family A (ABC1), member 13 |
| 别名 | ABCA13 |
| 计算分子量 | 576 kDa |
| 观测分子量 | 576 kDa |
| GenBank蛋白编号 | NM_152701 |
| 基因名称 | ABCA13 |
| Gene ID (NCBI) | 154664 |
| RRID | AB_3669314 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q86UQ4 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
ABCA13 belongs to the ABC transporter superfamily. ABCA13 is a transmembrane protein with the typical structure of ABC proteins: two transmembrane domains and two nucleotide-binding domains. ABCA13 may mediate the cholesterol and gangliosides transport from the plasma membrane to intracellular vesicles in an ATP hydrolysis-dependent manner, thus playing a role in their internalization by endocytic retrograde transport (PMID: 33478937). ABCA13 is expressed in the human trachea, testis, and bone marrow(PMID:12697998).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for ABCA13 antibody 19764-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |