验证数据展示
经过测试的应用
| Positive WB detected in | mouse brain tissue, rat brain tissue |
Planning an IHC experiment? We recommend our IHCeasy RBFOX1/A2BP1 Ready-To-Use IHC Kit. RBFOX1/A2BP1 primary antibody included.
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
85732-2-RR targets A2BP1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 | A2BP1 fusion protein Ag18527 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | ataxin 2-binding protein 1 |
| 别名 | FOX1, RBFOX1, A2BP, Ataxin-2-binding protein 1, Fox-1 homolog A |
| 计算分子量 | 395 aa, 42 kDa |
| 观测分子量 | 45-60 kDa |
| GenBank蛋白编号 | BC113691 |
| 基因名称 | A2BP1 |
| Gene ID (NCBI) | 54715 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q9NWB1 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
A2BP1, also named as FOX1 and HRNBP1, contains one RRM (RNA recognition motif) domain. A2BP1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. A2BP1 and ataxin-2 are both localized in the trans-Golgi network.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for A2BP1 antibody 85732-2-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |