Recombinant Rat ORM1 protein (rFc Tag)
种属
Rat
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Rat ORM1 protein Gln19-Pro205 (Accession# P02764) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 24614 |
| 蛋白编号 | P02764 |
| 预测分子量 | 47.2 kDa |
| SDS-PAGE | 55-70 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Alpha-1-acid glycoprotein 1 (AGP1), also called orosomucoid-1 (ORM1), is a glycoprotein synthesized mostly by hepatocytes and present in human plasma. ORM1 is an acute-phase reactant protein controlled by glucocorticoids, interleukin-1 and interleukin-6, and increase up to 5-50 times upon infection and/or inflammation. Anti-apoptotic effect and role as immunomodulator of ORM have been reported. ORM is an important carrier for synthetic drugs and influences their distribution and availability in the body.
参考文献:
1. Chen, Jie et al. Organogenesis vol. 21,1 (2025): 2519614. 2. Yu, Gang et al. Scientific reports vol. 13,1 15687. 21 Sep. 2023. 3. Yan, Nana et al. Hepatology (Baltimore, Md.), 10.1097/HEP.0000000000001737. 9 Mar. 2026. 4. Kim, Young-Eun et al. Frontiers in immunology vol. 14 1148574. 8 Sep. 2023.
