Recombinant Mouse RAB5A protein (rFc Tag)
种属
Mouse
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Mouse RAB5A protein Met1-Asn215 (Accession# Q9CQD1) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 271457 |
| 蛋白编号 | Q9CQD1 |
| 预测分子量 | 49.2 kDa |
| SDS-PAGE | 48-54 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
RAB5A is a core member of the Rab family within the Ras superfamily of small GTPases and a marker protein for early endosome formation. Localized in the cell membrane and early endosome membrane, RAB5A acts as a molecular switch regulating the docking and fusion of endocytic vesicles, making it a key regulator of the endocytic pathway.
参考文献:
1. Itoh, Takashi et al. Genes to cells : devoted to molecular & cellular mechanisms vol. 11,9 (2006): 1023-37. 2. Barbosa, M D et al. Mammalian genome : official journal of the International Mammalian Genome Society vol. 7,2 (1996): 166-7. 3. Cong, Xiao Xia et al. Cell death and differentiation vol. 27,8 (2020): 2344-2362.
