Recombinant Mouse MAG protein (rFc Tag)
种属
Mouse
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Mouse MAG protein Gly20-Pro516 (Accession# P20917-1) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 17136 |
| 蛋白编号 | P20917-1 |
| 预测分子量 | 80.4 kDa |
| SDS-PAGE | 90-120 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Myelin-associated glycoprotein (MAG) is a type I trans-membrane glycoprotein that belongs to the immunoglobulin (Ig) super-family. It contains five extracellular Ig-like domains, a single trans-membrane segment and one of two alternatively spliced cytoplasmic tails. MAG is expressed exclusively by myelinating glia—oligodendrocytes in the central nervous system (CNS) and Schwann cells in the peripheral nervous system (PNS)—where it localises to the periaxonal, non-compacted regions of the myelin sheath.
参考文献:
Schnaar, Ronald L, and Pablo H H Lopez. Journal of neuroscience research vol. 87,15 (2009): 3267-76.
