Recombinant Human MUC13 protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human MUC13 protein Thr19-Leu421 (Accession# Q9H3R2) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 56667 |
| 蛋白编号 | Q9H3R2 |
| 预测分子量 | 68.2 kDa |
| SDS-PAGE | 88-95 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Mucins (MUC) are highly glycosylated proteins that are abundantly expressed in mammalian epithelial cells. Mucin 13 (MUC13) is a member of the transmembrane glycoprotein mucins, which are normally expressed in the large intestine, trachea, kidney, small intestine, and gastric epithelium. MUC13 is involved in the tumorigenesis of multiple malignancies, including pancreatic cancer, colorectal cancer, renal cancer, and lung cancer.
参考文献:
1. Chauhan, Subhash C et al.Mol Cancer Ther. vol. 11,1 (2012): 24-33. 2. Pang, Yao et al. Oncology letters vol. 23,1 (2022): 37. 3. Sheng, Yong Hua et al. Oncogene vol. 38,48 (2019): 7294-7310.
