Recombinant Human XPNPEP2 protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human XPNPEP2 protein His22-Ala649 (Accession# O43895) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 7512 |
| 蛋白编号 | O43895 |
| 预测分子量 | 96.3 kDa |
| SDS-PAGE | 90-120 kDa , reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
XPNPEP2 (also known as aminopeptidase P or APP2) is a membrane-bound metalloprotease that catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, for example, Arg-Pro-Pro. It is a proline hydrolytic enzyme that hydrolyzes several biologically active peptides and causes a loss of substrate activity. XPNPEP2 expression was significantly upregulated in cervical cancer tissues compared with normal cervical tissues and cervical intraepithelial neoplasm tissues.
参考文献:
1.Cheng, Teng et al. Tumour Biol. 2017;39(7):1010428317717122. 2.Sprinkle, T J et al. Genomics vol. 50,1 (1998): 114-6.
