Recombinant Human P-cadherin protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human P-cadherin protein Asp108-Phe440 (Accession# P22223-1) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 1001 |
| 蛋白编号 | P22223-1 |
| 预测分子量 | 62.5 kDa |
| SDS-PAGE | 65-80 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. P-cadherin (placental cadherin), also known as CDH3 (cadherin 3), is a classical member of the cadherin superfamily, which also includes E-, N-, R-, and B-cadherins. Aberrant expression of P-cadherin has been reported in many cancers, including breast, gastric, endometrial, ovarian, and prostate cancer.
参考文献:
1.Angst, B D et al. Journal of cell science vol. 114,Pt 4 (2001): 629-41. 2.Tiwari, Prince et al. Advances in experimental medicine and biology vol. 1112 (2018): 107-138. 3.Vieira, André Filipe, and Joana Paredes. Molecular cancer vol. 14 178. 6 Oct. 2015 4.Paredes, Joana et al. Breast cancer research : BCR vol. 9,5 (2007): 214.
