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Recombinant Human CCL18 protein (rFc Tag)(HPLC verified)

种属

Human

纯度

>90 %, SDS-PAGE
>90%, SEC-HPLC

标签

rFc Tag

生物活性

未测试

Cat no : Eg5093

Print datasheet

Synonyms

CCL18/MIP-4, MIP 4, MIP-4, Alternative macrophage activation-associated CC chemokine 1, AMAC-1

验证数据展示

  • Purity of Recombinant Human CCL18 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human CCL18 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

  • The purity of Human CCL18 was greater than 90% as determined by SEC-HPLC.

    The purity of Human CCL18 was greater than 90% as determined by SEC-HPLC.

产品信息

纯度 >90 %, SDS-PAGE
>90%, SEC-HPLC
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Human CCL18 protein Ala21-Ala89 (Accession# P55774) with a rabbit IgG Fc tag at the N-terminus.
基因ID 6362
蛋白编号 P55774
预测分子量 35.0 kDa
SDS-PAGE 35-40 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

CCL18 is a small cytokine belonging to the CC chemokine family. The effector functions that CCL18 exerts on the immune system is mainly on the adaptive immune system, while being produced and secreted mainly by innate immune system. Although the functions of CCL18 have been well studied in vitro, physiological effects of CCL18 in vivo have been difficult to characterize because there is no murine analog of CCL18. Only recently has the receptor for CCL18 been identified, and further characterization of CCL18 interactions with its receptor will lead to better understanding of the physiological role of CCL18 in humans.

参考文献:

1. Korbecki J, et al. (2020). Int J Mol Sci. 21(21):7955.
2. Islam SA, et al. (2013). J Exp Med. 210(10):1889-98.
3. de Nadaï P, et al. (2006). J Immunol. 176(10):6286-93.
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