Recombinant Human ALCAM protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human ALCAM protein Trp28-Lys527 (Accession# Q13740) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 214 |
| 蛋白编号 | Q13740 |
| 预测分子量 | 82.1 kDa |
| SDS-PAGE | 88-100 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Activated leukocyte cell adhesion molecule (ALCAM, also known as CD166) is a cell adhesion molecule that belongs to the immunoglobulin superfamily. It is involved in cell-cell adhesion through homophilic and heterophilic (to CD6) interactions. ALCAM is widely expressed in a variety of normal tissues. Altered ALCAM expression has been associated with the differentiation state and progression in some neoplasms including melanoma, prostate, colorectal, and breast cancers.
参考文献:
1. Hong X, et al. (2010) J Surg Oncol. 101(7):564-569. 2. Ihnen M, et al. (2008) Breast Cancer Res Treat. 112(3):419-427. 3. Xie Y, et al. (2024) Nat Commun. 15(1):10889. 4. Ferragut F, et al. (2021) Cytokine Growth Factor Rev. 61:27-37. 5. Weidle UH, et al. (2010) Cancer Genomics Proteomics. 7(5):231-243.
