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Recombinant Human Stanniocalcin 2 protein (rFc Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg3119

Print datasheet

Synonyms

stanniocalcin 2, STC2, Stanniocalcin related protein, Stanniocalcin-2, Stanniocalcin-related protein

验证数据展示

  • Purity of Recombinant Human Stanniocalcin 2 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human Stanniocalcin 2 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human Stanniocalcin 2 protein Thr25-Arg302 (Accession# O76061) with a rabbit IgG Fc tag at the C-terminus.
基因ID 8614
蛋白编号 O76061
预测分子量 56.7 kDa
SDS-PAGE 55-65 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

STC2 (Stanniocalcin 2) belongs to the highly conserved family of secreted glycoprotein hormones, which are glycoproteins. STC2 acts as a glycosylated disulfide-linked dimeric protein hormone that regulates calcium and phosphate secretion. STC2 is highly expressed in breast, muscle, cardiac, testicular and pancreatic tissues, and plays a role in a wide variety of biological processes, including calcium and phosphate regulation, cytoprotection, cell development and angiogenesis. STC2 expression appears significantly altered in a variety of tumor cells and tumor tissues, suggesting that it may be involved in tumorigenesis, development and prognosis. (PMID: 36764215)

参考文献:

1.Jiang K, et al. Redox Biol. 2023;60:102626.                                                                
2. Qie S, Sang N. J Exp Clin Cancer Res. 2022;41(1):161.                                         
3. Jiang ZH, et al. Front Genet. 2022;13:927046.