• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
Use Able AI chat for product recommendations

Recombinant Human PLAP protein (rFc Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg3065

Print datasheet

Synonyms

PLAP, ALP, ALPP, EC:3.1.3.1, PALP

验证数据展示

  • Purity of Recombinant Human PLAP was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human PLAP was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Human PLAP protein Ile23-Asp506 (Accession# P05187) with a rabbit IgG Fc tag at the C-terminus.
基因ID 250
蛋白编号 P05187
预测分子量 78.8 kDa
SDS-PAGE 72-95 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

ALPP (Alkaline Phosphatase, Placental Type) is an alkaline phosphatase (ALP) isoenzyme, a heat-stable enzyme, which is highly abundant in the placenta. It is a membrane-bound glycoprotein that catalyzes the hydrolysis of monoesters of phosphoric acid at alkaline pH, and zinc and magnesium are important cofactors for ALPP. ALPP expression is highly restricted in normal tissues, but their expression levels are elevated in certain cancer types, making them potential targets with tumor specificity.

参考文献:

1. Wennberg C,et al. Hum Mutat. 2002;19(3):258-67.                                                 
2. Niida T, et al. J Thromb Thrombolysis. 2024;57(2):204-211.                                         
3. Bellazi L, et al. Placenta. 2010;31(9):764-9.
||
New chat Able
正在加载，请稍候...