Recombinant Mouse S100A8 protein (rFc Tag)
种属
Mouse
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Mouse S100A8 protein Pro2-Glu89 (Accession# P27005) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 20201 |
| 蛋白编号 | P27005 |
| 预测分子量 | 35.7 kDa |
| SDS-PAGE | 37-47 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
S100A8 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. S100A8 may form homodimer or heterodimer with S100A9(16216873).
参考文献:
1. Li Y, Chen B, et al. (2019) Circulation. 140(9):751-764. 2. Tousif S, Singh AP, et al. (2023) Circ Res. 132(3):267-289. 3. Cho E, Mun SJ, et al. (2024) Acta Pharmacol Sin. 45(3):581-593. 4. Guo Q, Zhao Y, et al. (2021) Cell Host Microbe. 29(2):222-235.e4.
