Recombinant Human IL-29 protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human IL-29 protein Gly20-Thr200 (Accession# Q8IU54) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 282618 |
| 蛋白编号 | Q8IU54 |
| 预测分子量 | 45.6 kDa |
| SDS-PAGE | 52-62 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Interleukin-29 (IL-29) is a cytokine belonging to the Type III interferon family, which has another two subfamilies IL-28A and IL28B. IL-29 is also known as IFN-λ1. It's produced predominantly by maturing dendritic cells and macrophages. IL-29 plays an important role in the immune response against pathogenes and especially against viruses by mechanisms similar to type I interferons. IL-29 receptes signals through JAK-STAT pathways leading to activated expression of interferon-stimulated genes and production of antiviral proteins.
参考文献:
1. Yoshitaka Hosokawa. et al. (2017) Immunol Invest. 46(6):615-624. 2. Katrin Witte et al. (2010) Cytokine Growth Factor Rev. 21(4):237-51. 3. Noah E Kelm. et al. (2016) Crit Rev Oncol Hematol. 106:91-8. 4. Jia-Min Wang. et al. (2019)J Cell Mol Med. 23(12):7926-7932.
