Recombinant Human IL-22RA2 protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human IL-22RA2 protein Thr22-Pro231 (Accession# Q969J5-2) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 116379 |
| 蛋白编号 | Q969J5-2 |
| 预测分子量 | 50.7 kDa |
| SDS-PAGE | 62-80 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
The IL-22 binding protein (IL-22BP) is encoded by the IL22RA2 gene. IL-22BP has been shown to be expressed by distinct dendritic cell populations in mesenteric lymph nodes and the gut of rodents. It has also been recently shown that IL-22BP expressed by T cells plays an important role for IBD development in humans and IBD mouse models.
参考文献:
1. Martin JC. et al. (2014). Mucosal Immunol. 7:101–113. 2. Huber S. et al. (2012). Nature. 491:259–263. 3. Pelczar P. et al. (2016). Science. 354:358–362.
