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Recombinant Human FGL1 protein (rFc Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg2765

Print datasheet

Synonyms

Hepassocin, fibrinogen like 1, Fibrinogen like protein 1, Fibrinogen-like protein 1, Hepatocyte-derived fibrinogen-related protein 1



产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性
Not tested
来源 HEK293-derived Human FGL1 protein Leu23-Ile312 (Accession# Q08830) with a rabbit IgG Fc tag at the C-terminus.
基因ID 2267
蛋白编号 Q08830
预测分子量 60 kDa
SDS-PAGE 55-65 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in 20mM Tris, 300mM NaCl ,pH8.0. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Fibrinogen-like 1 (FGL1), also termed hepatocyte-derived fibrinogen-related protein 1 (HFREP1) or hepassocin, is a predominantly liver expressed protein that has been implicated as both a hepatoprotectant and a hepatocyte mitogen. FGL1 expression is decreased in hepatocellular carcinoma (HCC), and it may play a role in the development of hepatocellular carcinomas.

参考文献:

1. Hara, H et al. Biochimica et biophysica acta vol. 1520,1 (2001): 45-53. 2. Li, Chang-Yan et al. Gut vol. 59,6 (2010): 817-26. 3. Chen, Jiongming et al. Biomarker research vol. 12,1 53. 31 May. 2024.

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