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Recombinant Mouse SDC2 protein (rFc Tag)

种属

Mouse

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg2700

Print datasheet

Synonyms

CD362, Fibroglycan, Heparan sulfate proteoglycan core protein, HSPG, Hspg1

验证数据展示

  • Purity of Recombinant Mouse SDC2 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Mouse SDC2 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Mouse SDC2 protein Glu19-Glu145 (Accession# P43407) with a rabbit IgG Fc tag at the C-terminus.
基因ID 15529
蛋白编号 P43407
预测分子量 39.9 kDa
SDS-PAGE 45-65 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

SDC2, containing cell surface heparan sulfate proteoglycan, functions as an integral membrane protein and participates in cell proliferation, cell migration, cell adhesion and signal transduction. It has been reported that the expression level of SDC2 will be up-regulated under hypoxia condition which can induce increased release of cytokines and chemokines. Besides, methylated SDC2 can be used as a potential biomarker for early diagnosis of colon cancer.

参考文献:

1.Kaur C, et al. (2009). Glia. 57(3):336-49.
2.Mytilinaiou M, et al. (2013). IUBMB Life. 65(2):134-43.
3.Nikolaou S, et al. (2018). Tech Coloproctol. 22(7):481-498. 
4.Molnár B, et al. (2018). BMC Cancer. 27;18(1):695.