Recombinant Mouse Ngfr protein (rFc Tag)
种属
Mouse
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <1.0 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Mouse Ngfr protein Lys32-Asp252 (Accession# Q9Z0W1-1) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 18053 |
| 蛋白编号 | Q9Z0W1-1 |
| 预测分子量 | 49.1 kDa |
| SDS-PAGE | |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
NGFR, also named as TNFRSF16, Gp80-LNGFR, p75 ICD and CD271, a member of the tumor necrosis factor superfamily. It is highly expressed in both neurons and glial cells during CNS development and after brain injury, whereas in normal adulthood, it is present only in specific brain regions such as neurons and astrocytes of hippocampal and especially in the cholinergic neurons of the basal forebrain. NGFR can mediate cell survival or cell death, can promote or inhibit axonal growth, and can facilitate or attenuate proliferation, depending on the cell context.
参考文献:
1.Cragnolini, Andrea B, and Wilma J Friedman. Trends in neurosciences vol. 31,2 (2008): 99-104. 2.Chen, Mingming et al. Cellular and molecular neurobiology vol. 42,4 (2022): 1153-1166. 3.Yang, Chun-Rui et al. FASEB journal vol. 36,3 (2022): e22180. 4.Ali, Naif H et al. Molecular neurobiology vol. 61,5 (2024): 2469-2480. 5.Xie, Bo et al. Frontiers in cell and developmental biology vol. 11 (2023): 1283878.
