Recombinant Mouse CD147 protein (rFc Tag)
种属
Mouse
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
纯度 | >90 %, SDS-PAGE |
内毒素 | <0.1 EU/μg protein, LAL method |
生物活性 | Not tested |
来源 | HEK293-derived Mouse CD147 protein Ala22-Arg325 (Accession# P18572-1) with a rabbit IgG Fc tag at the C-terminus. |
基因ID | 12215 |
蛋白编号 | P18572-1 |
预测分子量 | 59.6 kDa |
SDS-PAGE | 67-90 kDa, reducing (R) conditions |
组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
CD147, also known as Basigin or extracellular matrix metalloproteinase inducer (EMMPRIN), is a transmembrane glycoprotein that belongs to the immunoglobulin superfamily. The molecule is composed of an intracellular portion, an extracellular portion and a single transmembrane region. CD147 is expressed on a variety of cell types (e.g., hematopoietic, epithelial, and endothelial cells) and at varying levels. CD147 is a pleiotropic molecule that plays an important role in fetal, neuronal, lymphocyte and extracellular matrix development.
参考文献:
1. C Biswas, et al. (1995) Cancer Res. Jan 15;55(2):434-9. 2. Hsiang-Chi Tseng, et al. (2020) Nat Commun. Sep 23;11(1):4810. 3. Kathryn T Iacono, et al. (2007) Exp Mol Pathol. Dec;83(3):283-95.