• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

Recombinant Human DCIR/CLEC4A protein (rFc Tag)

种属

Human

纯度

>95 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg1350

Print datasheet

Synonyms

CLEC4A, CD367, CLECSF6, DCIR, DDB27

验证数据展示

  • Purity of Recombinant Human DCIR was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human DCIR was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >95 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human DCIR protein Gln70-Leu237 (Accession# Q9UMR7-1) with a rabbit IgG Fc tag at the N-terminus.
基因ID 50856
蛋白编号 Q9UMR7-1
预测分子量 47.1 kDa
SDS-PAGE 45-60 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

C-type lectin domain family 4 member A (CLEC4A) is also known as DCIR, HDCGC13P, CLECSF6, and CD367. CLEC4A is C-type lectin receptor that binds carbohydrates mannose and fucose but also weakly interacts with N-acetylglucosamine (GlcNAc) in a Ca2+-dependent manner. It is involved in regulating immune reactivity. In plasmacytoid dendritic cells, CLEC4A inhibits TLR9-mediated IFNA and TNF production.

参考文献:

1.Nagae M, et al. (2016) FEBS Lett. 590(8):1280-8.
2.Bates EE, et al. (1999) J Immunol. 163(4):1973-83.
3.Meyer-Wentrup F, et al. (2008) Blood. 111(8):4245-53.