Recombinant Human Coagulation factor II protein (His Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
His Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human Coagulation factor II protein Ala44-Glu622 (Accession# P00734) with a His tag at the C-terminus. |
| 基因ID | 2147 |
| 蛋白编号 | P00734 |
| 预测分子量 | 66.1 kDa |
| SDS-PAGE | 68-90 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Coagulation factors are a group of related proteins that are essential for normal blood clotting (haemostasis). After an injury, clots protect the body by sealing off damaged blood vessels and preventing further blood loss. Prothrombin circulates in the bloodstream in an inactive form until an injury occurs. In response to that, prothrombin is converted to its active form, thrombin. Thrombin next converts a protein called fibrinogen into fibrin. Thrombin is also important for cell growth and division, tissue repair, and new blood vessels formation - angiogenesis.
参考文献:
1.Akhavan, S et al.Thrombosis and haemostasis vol. 84,6 (2000): 989-97. 2.Danckwardt, Sven et al. Acta haematologica vol. 115,3-4 (2006): 192-7. 3.Jayandharan, G et al. Journal of thrombosis and haemostasis : JTH vol. 3,7 (2005): 1446-53. 4.McGlennen, Ronald C, and Nigel S Key.Archives of pathology & laboratory medicine vol. 126,11 (2002): 1319-25.
