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Recombinant Human B3GAT1/CD57 protein (His Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

His Tag

生物活性

未测试

Cat no : Eg0793

Print datasheet

Synonyms

B3GAT1, Beta-1,3-glucuronyltransferase 1, EC:2.4.1.135, Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, GLCATP

验证数据展示

  • Purity of Recombinant Human B3GAT1 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human B3GAT1 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human B3GAT1 protein Thr28-Ile334 (Accession# Q9P2W7-1) with a His tag at the N-terminus.
基因ID 27087
蛋白编号 Q9P2W7-1
预测分子量 36.1 kDa
SDS-PAGE 38-45 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

B3GAT1, or beta-1,3-glucuronyltransferase 1, is a gene located in humans that encodes a member of the glucuronyltransferase gene family. This enzyme plays a critical role in the biosynthesis of the carbohydrate epitope HNK-1 (human natural killer-1), also known as CD57 and LEU7. Research has implicated B3GAT1 in various disorders, particularly those related to the immune system and infections. For instance, the enzyme's role in synthesizing glycosaminoglycans contributes to the structural integrity of cellular surfaces, which can influence susceptibility to viral infections.

参考文献:

1.Yasuhiko Kizuka, et al. (2021) Glycoscience Protocols. 
2.Trimarco JD, et al. (2022) Nat Commun. 3 (1):6456.