Recombinant Mouse EMR1/ADGRE1/(F4/80) protein (His Tag)
种属
Mouse
纯度
>90 %, SDS-PAGE
标签
His Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Mouse EMR1/ADGRE1/(F4/80) protein Gln28-Glu644 (Accession# Q61549) with a His tag at the C-terminus. |
| 基因ID | 13733 |
| 蛋白编号 | Q61549 |
| 预测分子量 | 67.7 kDa |
| SDS-PAGE | kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Mouse F4/80, also named as EMR1 and Gpf480, is a 160-kDa cell surface glycoprotein which is a member of the EGF TM7 family. The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, including Kupffer cells in liver, splenic red pulp macrophages, brain microglia, gut lamina propria and Langerhans cells in the skin. The function of F4/80 is unclear, but it is speculated to be involved in macrophage adhesion events, cell migration or as a G protein-coupled signaling component of macrophages.
参考文献:
1.J M Austyn, et al. (1981) Eur J Immunol. 11(10):805-15. 2.A J McKnight, et al. (1996) J Biol Chem. 271(1):486-9. 3.I D Haidl, et al. (1996) Eur J Immunol. 26(5):1139-46. 4.Siamon Gordon, et al. (2011) Eur J Immunol. 41(9):2472-6.
